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SJ-500手提式基因槍

簡要描述:SJ-500手提式基因槍主要用于體內(nèi)細胞生長和發(fā)育機理的研究,特別是基因治療和基因免疫(基因疫苗)的應(yīng)用。

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  • 更新時間:2023-03-08
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SJ-500手提式基因槍主要技術(shù)參數(shù):
實驗條件::原位、體外、體內(nèi)、來自體內(nèi)
目標(biāo)區(qū)域:2cm2
壓力范圍:0.5-5MPa(每彈倉12次)
目標(biāo)類型:
動物:任何可暴露于基因槍口外的組織(皮膚、器官);細胞、外植體和器官培養(yǎng)
植物:田間和溫室使用、植物培養(yǎng)細胞和外植體
酵母、細菌、其它微生物
電 壓:9V(可發(fā)射1000次)
氣 源:氦氣
金屬顆粒:Φ0.6-1.6μm(常用Φ1.6 μm)
SJ-500手提式基因槍主要用于體內(nèi)細胞生長和發(fā)育機理的研究,特別是基因治療和基因免疫(基因疫苗)的應(yīng)用。這種微型基因槍不攜帶病毒和毒性化合物并適度轉(zhuǎn)運基因物質(zhì)進入不同細胞或器官,與其它基因?qū)胂到y(tǒng)相比具有安全、方便、高效等明顯的優(yōu)勢。
采用金微粒子彈為載體轉(zhuǎn)運DNA或RNA進入動物或人體的皮膚組織,它使轉(zhuǎn)基因工作在操作上變得更靈活,簡便。軍事醫(yī)學(xué)科學(xué)院放射研究所用此設(shè)備開展科研工作,取得很好結(jié)果,其論文發(fā)表在《生物技術(shù)通訊》2001年第四期,“基因槍在大鼠閉塞性血管病基因治療中的應(yīng)用”。“用CpG ODN增強基因槍接種DNA疫苗THI型免疫應(yīng)答的研究”,由復(fù)旦大學(xué)上海醫(yī)學(xué)院在國外發(fā)表。

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